Scanning electron microscopy reveals the intricate surface details of biological specimens that optical microscopes cannot resolve. From the ultrastructure of cell membranes to the complex morphology of insects, SEM provides unparalleled depth of field and three-dimensional visualization of biological samples.

The SNE-Alpha desktop SEM enables biological imaging without the complexity of traditional floor-model systems. Variable pressure mode allows imaging of hydrated and delicate specimens with minimal preparation, while the compact design fits easily in teaching labs and research facilities.

Key Biology Applications

• Microbiology: Image bacteria, fungi, and biofilms at high resolution. Study cell morphology, attachment mechanisms, and antimicrobial effects
• Cell Biology: Visualize cell surface features, membrane structures, and cell-cell interactions in fixed preparations
• Entomology: Study insect morphology, compound eyes, wing scales, sensory structures, and surface textures
• Botany: Examine plant surfaces, stomata, trichomes, pollen grains, and seed coat structures
• Parasitology: Characterize parasite morphology, attachment structures, and surface antigens
• Marine Biology: Image diatoms, foraminifera, and other microorganisms with shell structures

Sample Preparation for Biological Specimens

Biological samples typically require preparation to withstand the vacuum environment and electron beam. Common preparation methods include:

• Chemical Fixation: Glutaraldehyde and osmium tetroxide preserve cellular ultrastructure
• Critical Point Drying: Prevents surface tension artifacts during drying
• Sputter Coating: Apply thin gold or platinum layer to prevent charging on non-conductive samples
• Variable Pressure Mode: Image hydrated samples with reduced preparation requirements